Idarucizumab (dabigatran etexi

Idarucizumab (dabigatran etexilate mesylate) 抗体, 单克隆，Idarucizumab (dabigatran etexilate mesylate) Antibody, Monoclonal，Idarucizumab (dabigatran etexilate mesylate) 抗体, 单克隆,Idarucizumab (dabigatran etexilate mesylate) Antibody, Monoclonal

产品名称：Idarucizumab (dabigatran etexilate mesylate) 抗体, 单克隆-Idarucizumab (dabigatran etexilate mesylate) Antibody, Monoclonal

产品货号：PSI-10-593-0.1mg

产品规格：0.1mg

背景资料：Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its anticoagulant effect. As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease, concomitant NSAID or warfarin use, etc).Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of dabigatran-associated bleeding in life-threatening or surgically induced situations. Its use is associated with immediate, fully and sustained reversal of the anticoagulant effects of dabigatran.Idarucizumab protein structure can be viewed below, with disulfide bridges at the following points: H22-H95, H149-H205, H225-L-219, L23-L93, L139-L199.

保存建议：Idarucizumab (dabigatran etexilate mesylate) 抗体, 单克隆-Idarucizumab (dabigatran etexilate mesylate) Antibody, MonoclonalStore at -80℃

应用类型：

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