ITCH 抗体-ITCH Antibody

ITCH 抗体，ITCH Antibody，ITCH 抗体,ITCH Antibody

产品名称：ITCH 抗体-ITCH Antibody

产品货号：PSI-7645-0.02mg

产品规格：0.02mg

背景资料：The Itchy E3 ubiquitin protein ligase (ITCH) is a member of the Nedd4 family of HECT domain E3 ubiquitin ligases (1). HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. ITCH plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses (2). In B cells, ITCH is thought to associate with latent membrane protein 2A (LMP2A) of Epstein-Barr virus, specifically down-regulating its activity in B cell signaling (3). Mutations in this gene are a cause of syndromic multisystem autoimmune disease (4).

保存建议：ITCH 抗体-ITCH Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB

点击：ITCH 抗体-ITCH Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。