IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN.<br>The immunogen is located within the last 50 amino acids of IL-36RN.
保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
背景资料:IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).