AXIN2 抗体-AXIN2 Antibody

AXIN2 抗体，AXIN2 Antibody，AXIN2 抗体,AXIN2 Antibody

产品名称：AXIN2 抗体-AXIN2 Antibody

产品货号：PSI-6163-0.02mg

产品规格：0.02mg

背景资料：AXIN2 Antibody: Like the related protein AXIN1, AXIN2 is thought to play an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway. In mouse, AXIN2 organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and AXIN2, which leads to the degradation of beta-catenin, which is thought to be an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.

保存建议：AXIN2 抗体-AXIN2 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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