Cyclin O 抗体-Cyclin O Antibody

Cyclin O 抗体，Cyclin O Antibody，Cyclin O 抗体,Cyclin O Antibody

产品名称：Cyclin O 抗体-Cyclin O Antibody

产品货号：PSI-3859-0.02mg

产品规格：0.02mg

背景资料：Cyclin O Antibody: Cyclin O, also known as CCNO, has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells. Cyclin O binds to and activates Cdk2 in response to instrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents. Supression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact. Note: this gene, which had a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase. A later publication identified this gene's product as a cyclin protein family member.

保存建议：Cyclin O 抗体-Cyclin O Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB

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