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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Rabbit Rheb polyclonal antibody was raised against a 14 amino acid synthetic peptide from the amino terminus of human Rheb.<br>The immunogen is located within the first 50 amino acids of Rheb.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB
- 抗体英文名:
Rheb Antibody
- 抗体名:
Rheb Antibody
- 规格:
0.02mg
Rheb 抗体,Rheb Antibody,Rheb 抗体,Rheb Antibody
产品名称:Rheb 抗体-Rheb Antibody
产品货号:PSI-3499-0.02mg
产品规格:0.02mg
背景资料:Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.
保存建议:Rheb 抗体-Rheb Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB
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