- ￥22
- ProSci
- 美国
- PSI-3485-0.02mg
- 2025年07月10日
- E, WB, ICC
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TOR antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human TOR.<br>The immunogen is located within amino acids 210 - 260 of TOR.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB, ICC
- 抗体英文名：
TOR Antibody
- 抗体名：
TOR Antibody
- 规格：
0.02mg
TOR 抗体，TOR Antibody，TOR 抗体,TOR Antibody
产品名称：TOR 抗体-TOR Antibody
产品货号：PSI-3485-0.02mg
产品规格：0.02mg
背景资料：TOR Antibody: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. It was initially discovered as a kinase whose ability to stimulate T cell proliferation in response to IL-2 could be inhibited by the immunosuppressive drug rapamycin. Rapamycin inhibits TOR in other cell types resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with the regulatory proteins RAPTOR and GbetaL. Its downstream targets are thought to be the ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins (4EBPs). Regulation of these protein families allows TOR to control protein biosynthesis.
保存建议：TOR 抗体-TOR Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB, ICC
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文献和实验Nutritional Control of Cell Growth via TOR Signaling in Budding Yeast
Cell growth is highly regulated and its deregulation is related to many human diseases such as cancer. Nutritional cues stimulate cell growth through modulation of TOR (target of rapamycin) signaling pathway. At the center of this pathway
Assessing Cell Size and Cell Cycle Regulation in Cells with Altered TOR Activity
Target of rapamycin (TOR) regulates the growth of cells and organisms. Numerous growth-promoting and growth-arresting pathways converge on TOR; TOR acts as an important hub, balancing the pro- and anti-growth signals within a cell
The In Vivo Evaluation of Active-Site TOR Inhibitors in Models of BCR-ABL+ Leukemia
oncogene. We also discuss the application of these models to preclinical testing of active-site TOR inhibitors, a novel class of compounds that selectively target the ATP-binding pocket of the target of rapamycin (TOR) kinase.
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