MAP1 抗体-MAP1 Antibody

MAP1 抗体，MAP1 Antibody，MAP1 抗体,MAP1 Antibody

产品名称：MAP1 抗体-MAP1 Antibody

产品货号：PSI-3005-0.02mg

产品规格：0.02mg

背景资料：MAP1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.

保存建议：MAP1 抗体-MAP1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB

点击：MAP1 抗体-MAP1 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。