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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IRAK-M antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRAK-M.<br>The immunogen is located within the last 50 amino acids of IRAK-M.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P, IF
- 抗体英文名:
IRAK-M Antibody
- 抗体名:
IRAK-M Antibody
- 规格:
0.02mg
IRAK-M 抗体,IRAK-M Antibody,IRAK-M 抗体,IRAK-M Antibody
产品名称:IRAK-M 抗体-IRAK-M Antibody
产品货号:PSI-2355-0.02mg
产品规格:0.02mg
背景资料:IRAK-M Antibody: Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-betaB by IL-1/Toll receptors, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-betaB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS.
保存建议:IRAK-M 抗体-IRAK-M Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P, IF
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