IKK alpha 抗体-IKK alpha Antibod

IKK alpha 抗体，IKK alpha Antibody，IKK alpha 抗体,IKK alpha Antibody

产品名称：IKK alpha 抗体-IKK alpha Antibody

产品货号：PSI-2025-0.02mg

产品规格：0.02mg

背景资料：IKK alpha Antibody: Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFa, and bacteria product LPS. NF-κB is associated with IκB proteins in the cell cytoplasm, which inhibit NF-κB activity. The long-sought IκB kinase (IKK), which phosphorylates IκB, and mediates IκB degradation and NF-κB activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKα and IKKβ). IKKα and IKKβ interact with each other and both are essential for the NF-κB activation. IKKα specifically phosphorylates IkB-alpha. IKKα is expressed in variety of human tissues.

保存建议：IKK alpha 抗体-IKK alpha Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, ICC, IF

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