抗人 CD45 荧光标记PE 抗体

anti-human CD45 Antibody-PE详细如下：

Description ：CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocytecommon antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasmamembrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signalingmolecule that regulates a variety of cellular processes including cell growth, differentiation, cellcycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigenreceptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, andother Src family kinases. CD45 non-covalently associates with lymphocyte phosphataseassociated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bindgalectin-1 and to be associated with several other cell surface antigens including CD1, CD2,CD3, and CD4.

Verified Reactivity ：Human

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Human PBMC

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation ：The antibody was purified by affinity chromatography and conjugated with PE under optimalconditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)