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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD61
- 级别：
CD61 Antibody
- 目录编号：
CD61 Antibody
- 克隆性：
单克隆
- 抗原来源：
亚美尼亚仓鼠
- 保质期：
CD61 Antibody
- 抗体英文名：
anti-mouse/rat CD61 Antibody-PE
- 抗体名：
CD61 Antibody
- 标记物：
PE
- 宿主：
亚美尼亚仓鼠
- 适应物种：
小鼠、大鼠
- 免疫原：
CD61 Antibody
- 亚型：
CD61 Antibody
- 形态：
CD61 Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.2 mg/ml
- 规格：
50 µg/ 200 µg
| 规格： | 50 µg | 产品价格： | ￥2000.0 |
|---|---|---|---|
| 规格： | 200 µg | 产品价格： | ￥5200.0 |
anti-mouse/rat CD61 Antibody-PE详细如下：
Description ：CD61 is a 110 kD integrin β chain also known as β integrin or gpIIIa. It associates with theintegrin α chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate withthe integrin α chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets,megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts,and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin,fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelialadhesion is mediated by the binding of α /β integrin or vitronectin receptor to CD31 (PECAM1).
Verified Reactivity ：Mouse, Rat
Antibody Type ：Monoclonal
Host Species ：Armenian Hamster
Immunogen ：Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with PE under optimalconditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10 cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
Description ：CD61 is a 110 kD integrin β chain also known as β integrin or gpIIIa. It associates with theintegrin α chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate withthe integrin α chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets,megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts,and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin,fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelialadhesion is mediated by the binding of α /β integrin or vitronectin receptor to CD31 (PECAM1).
Verified Reactivity ：Mouse, Rat
Antibody Type ：Monoclonal
Host Species ：Armenian Hamster
Immunogen ：Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with PE under optimalconditions.
Concentration ：0.2 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10 cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Excitation Laser ：Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Kieffer N, et al. 1990. Annu. Rev. Cell Biol. 6:329. (Block)
2. Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
3. Ashkar S, et al. 2000. Science 287:860. (Block)
4. Schultz JF, et al. 1995. J. Biol. Chem. 270:11522. (Block)
5. Moulder K, et al. 1991. J. Exp. Med. 173:343. (Activ)
6. Carlson TR, et al. 2008.135:2193. PubMed
7. Yamaji D, et al. 2009. Genes Dev. 23:2382. PubMed
Product Citations：
1. Huang TC, et al. 2021. Nature. 600:737. PubMed
2. Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
3. Gawish R, et al. 2022. Elife. 11:. PubMed
4. Zhang J, et al. 2018. Nature. 562:595. PubMed
5. Li H, et al. 2021. Nat Commun. 12:2773. PubMed
6. Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed
7. Wang X, et al. 2021. Cell Res. 31:526. PubMed
8. Aizawa E, et al. 2022. Stem Cell Reports. 17:43. PubMed
9. Lin J, et al. 2021. Mol Med. 27:149. PubMed
10. Bonnardel J, et al. 2019. Immunity. 51:638. PubMed
11. Horiguchi H, et al. 2019. Genes Dev. 33:1641. PubMed
12. Bleckwehl T, et al. 2021. Nat Commun. 12:5771. PubMed
1. Kieffer N, et al. 1990. Annu. Rev. Cell Biol. 6:329. (Block)
2. Piali L, et al. 1995. J. Cell Biol. 130:451. (Block)
3. Ashkar S, et al. 2000. Science 287:860. (Block)
4. Schultz JF, et al. 1995. J. Biol. Chem. 270:11522. (Block)
5. Moulder K, et al. 1991. J. Exp. Med. 173:343. (Activ)
6. Carlson TR, et al. 2008.135:2193. PubMed
7. Yamaji D, et al. 2009. Genes Dev. 23:2382. PubMed
Product Citations：
1. Huang TC, et al. 2021. Nature. 600:737. PubMed
2. Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
3. Gawish R, et al. 2022. Elife. 11:. PubMed
4. Zhang J, et al. 2018. Nature. 562:595. PubMed
5. Li H, et al. 2021. Nat Commun. 12:2773. PubMed
6. Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed
7. Wang X, et al. 2021. Cell Res. 31:526. PubMed
8. Aizawa E, et al. 2022. Stem Cell Reports. 17:43. PubMed
9. Lin J, et al. 2021. Mol Med. 27:149. PubMed
10. Bonnardel J, et al. 2019. Immunity. 51:638. PubMed
11. Horiguchi H, et al. 2019. Genes Dev. 33:1641. PubMed
12. Bleckwehl T, et al. 2021. Nat Commun. 12:5771. PubMed
文献支持
抗小鼠/大鼠 CD61 荧光标记PE 抗体
￥2000 - 5200
