抗小鼠/人 Helios 荧光标记APC 抗体

anti-mouse/human Helios Antibody-APC详细如下：

Description ：Helios is a member of the Ikaros family of zinc finger transcription factors. It contains a Cterminal region composed of 2 zinc-finger domains that mediate dimerization between thefamily members. Helios was originally cloned from a mouse thymoma line. It is mainlyexpressed in peripheral T cells and thymocytes. It is found at high levels in a subpopulation ofregulatory T cells. Helios plays an important role in T cell development and homeostasis.Overexpression of Helios profoundly alters αβ T cell differentiation and activation. It has beendetermined that silencing of Helios in B cells is critical for maintaining normal B cell function.Helios is also involved in tumor immunity.

Verified Reactivity ：Mouse, Human

Antibody Type ：Monoclonal

Host Species ：Armenian Hamster

Immunogen ：Helios peptide (aa 51-107)

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation ：The antibody was purified by affinity chromatography, and conjugated with APC under optimalconditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：ICFC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by intracellular flow cytometry using our TrueNuclear™ Transcription Factor Staining Protocol.For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µlstaining volume or 5 µl per 100 µl of whole blood.It is recommended that the reagent be titrated foroptimal performance for each application.

Excitation Laser ：Red Laser (633 nm)