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- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
RT/2-8℃/-20℃
- 保质期：
3年
- 英文名：
EACA
- 库存：
999
- 供应商：
北京康瑞纳生物科技有限公司
- CAS号：
60-32-2
- 规格：
25g
6-氨基己酸 60-32-26-氨基己酸 60-32-2
产品名称：6-氨基正己酸 60-32-2
产品编号：A1154
中文别称 6-氨基正己酸
英文别称 6-Aminocaproic acid
CAS 60-32-2
分子式 C6H13NO2
分子量 131.17
储存条件 RT
有效期 3年
溶解性 250mg/mL in water
纯度 ≥99%
性状 白色粉末
包装 瓶
规格 25g 100g
描述 是抗纤维蛋白溶解剂,能抑制纤溶酶原激活剂。(It is an antifibrinolytic agent that inhibits plasminogen activator.)
靶点 Others
通路 Others
生物活性 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1-2].
In Vitro EACA (20-180 μg/mL) inhibits fibrinolysis in plasma of Asian elephants, with an effective concentration of 61.5 μg/mL[2].
In Vivo EACA (20-100 mg/kg; a single p.o.) inhibits fibrinolysis at all doses tested in dogs.EACA (20-100 mg/kg; a single p.o.) is rapidly absorbed (Tmax=1 h) and eliminated rapidly in dogs[3].
6-Aminohexanoic acid 60-32-26-Aminohexanoic acid 60-32-2
Product Name: 6-Aminohexanoic Acid 60-32-2
Product number: A1154
Chinese alias 6-aminohexanoic acid
English alias 6-Aminocaproic acid
CAS 60-32-2
Molecular formula C6H13NO2
Molecular weight 131.17
Storage conditions RT
Validity period of 3 years
Solubility 250mg/mL in water
Purity ≥ 99%
Appearance: White powder
Packaging bottle
Specification 25g 100g
Description: It is an anti fibrinolytic agent that can inhibit plasminogen activator. (It is an antagonistic agent that inhibits plasma activator.)
Other targets
Pathways Other
Bioactive 6-Aminocaproic acid (EACA), a monoamine carboxylic acid, is a potential and orally active inhibitor of plasma and plasminogen 6-Aminocaproic acid is a potential antifibrinolytic agent 6-Aminocaproic acid events clot analysis through the competitive binding of lysine residues on plasma, inhibiting plasma formation and reducing fibrinolysis 6-Aminocaproic acid can be used for the research of blending disorders [1-2]
In Vitro EACA (20-180 μ G/mL) inhibitors fibrosis in plasma of Asian elements, with an effective concentration of 61.5 μ G/mL [2]
In Vivo EACA (20-100 mg/kg; a single p.o.) inhibits fibrosis at all dos tested in dogs EACA (20-100 mg/kg; a single p.o.) is rapidly adsorbed (Tmax=1 h) and efficiently in dogs [3]
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文献和实验Ren L, Liu J, Liu C, Yang T, Wu X, Zhang X, Yang L, Xia J, Li W. AIn Vitro Cell（RAW264.7 cells；100 ng/mL LPS，24 h at 37 °C） RAW264.7 cells were seeded in confocal dishes at a density of 1 × 105 cells per dish. After the culture of 24 h, cells were treated with 100 ng/mL LPS in different media, including a control medium, PACDFe extract, and PACDFe hydrogel extract supplemented with 1 μM LL-37 for another 24 h at 1990 °C. 更多文献信息请详询客服
