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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD1d (CD1.1, Ly-38)
- 级别:
CD1d (CD1.1, Ly-38) Antibody
- 目录编号:
CD1d (CD1.1, Ly-38) Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
CD1d (CD1.1, Ly-38) Antibody
- 抗体英文名:
Purified anti-mouse CD1d (CD1.1, Ly-38) Antibody
- 抗体名:
CD1d (CD1.1, Ly-38) Antibody
- 标记物:
CD1d (CD1.1, Ly-38) Antibody
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
CD1d (CD1.1, Ly-38) Antibody
- 亚型:
CD1d (CD1.1, Ly-38) Antibody
- 形态:
CD1d (CD1.1, Ly-38) Antibody
- 应用范围:
FC, IHC, IP
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
500 µg
Purified anti-mouse CD1d (CD1.1, Ly-38) Antibody详细如下:
Description :CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structuralsimilarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans,CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III(CD1e). But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broadtissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes.CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. Ithas been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested、IHC, IP - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description :CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structuralsimilarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans,CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III(CD1e). But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broadtissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes.CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. Ithas been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation :The antibody was purified by affinity chromatography
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested、IHC, IP - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Fischer K, et al. 2004. P. Natl. Acad. Sci. USA 101:10685. (Block)
2. Brozovic S, et al. 2004. Nat. Med. 10:535.
3. Brossay L, et al. 1997. J. Immunol.. 159:1216. (Block)
4. Jiang J, et al. 2012. PLoS One. 7:47487. PubMed
Product Citations:
1. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
2. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
3. Jiang J, et al. 2012. PLoS One. 7:47487. PubMed
4. Noto Llana M, et al. 2017. Front Cell Infect Microbiol. 0.568055556. PubMed
1. Fischer K, et al. 2004. P. Natl. Acad. Sci. USA 101:10685. (Block)
2. Brozovic S, et al. 2004. Nat. Med. 10:535.
3. Brossay L, et al. 1997. J. Immunol.. 159:1216. (Block)
4. Jiang J, et al. 2012. PLoS One. 7:47487. PubMed
Product Citations:
1. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
2. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
3. Jiang J, et al. 2012. PLoS One. 7:47487. PubMed
4. Noto Llana M, et al. 2017. Front Cell Infect Microbiol. 0.568055556. PubMed
文献支持
Purified 抗小鼠 CD1d (CD1.1, Ly-38) 抗体
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