Description :CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structuralsimilarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans,CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III(CD1e). But CD1d is the only CD1 molecule has been found in mouse. Mouse CD1d has broadtissue distribution, and is found on leukocytes, dendritic cells, epithelial cells, and thymocytes.CD1d plays a role in non-peptide glycolipid antigen presentation to CD1d-restricted T cells. Ithas been shown that PKCδ is a critical regulator of CD1d-mediated antigen presentation.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Mouse Cd1.1 cDNA-transfected RMA-S mouse T lymphoma
Formulation :0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxinlevel is < 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
Preparation :The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration :The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentrationand expiration, please enter the lot number in our Certificate of Analysis online tool.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™solution contains no preservative; handle under aseptic conditions.
Application :FC - Quality tested、IHC, IP, Block - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per millioncells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance foreach application.