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- 2025年07月16日
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文献和实验Apoptosis: Molecular Regulation of Cell Death and Hematologic Malignancies
Apoptosis, or programmed cell death, represents in cell biology a functional program as important as cell growth or differentiation. Programmed cell death is of basic importance for the development of multicellular organisms and its basic
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
. Whereas interest in the apoptosis-inducing molecules TNF and Fas ligand has peaked because of their participation in events such as autoimmune disorders, activation-induced cell death, immune privilege, and tumor evasion from the immune system, another death-inducing family member
of apoptosis, or genetically encoded programmed cell death. Apoptosis is defined by distinct characteristic morphological and biochemical changes (1) . In malignant cells, these physiological apoptotic pathways are often altered, resulting in a significant
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