生物素抗人 CD267 (TACI) 抗体

Biotin anti-human CD267 (TACI) Antibody详细如下：

Description ：TACI, Transmembrane Activator CAML (calcium modulator and cyclophilin ligand) Interactor, isa 32 kD type III transmembrane protein. It belongs to TNF receptor superfamily, known asTNFRSF member 13B (TNFRSF13B) or CD267. TACI is expressed on B cells, and myelomacells. TACI contains 2 cysteine-rich domains (CRDs). Recent studies, however, have shownthat another shorter form (TACI_d2) of TACI exists wherein the N-terminal CRD is removed byalternative splicing. TACI_d2 contains full affinity for its ligands. Several proteins (BAFF/BLys,APRIL, Syndecan-2) have been identified as TACI ligands. The interaction of TACI with itsligands induces activation of the transcription factors NFAT, AP1, and NF-κ B and plays acrucial role in humoral immunity by negative regulation of B cell proliferation and survival.

Verified Reactivity ：Human

Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus

Antibody Type ：Monoclonal

Host Species ：Rat

Immunogen ：TACI-transfected RBL cells

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation ：The antibody was purified by affinity chromatography, and conjugated with biotin under optimalconditions.

Concentration ：0.5 mg/ml

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.