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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD80
- 级别：
CD80 Antibody
- 目录编号：
CD80 Antibody
- 克隆性：
单克隆
- 抗原来源：
仓鼠
- 保质期：
CD80 Antibody
- 抗体英文名：
Alexa Fluor® 488 anti-mouse CD80 Antibody
- 抗体名：
CD80 Antibody
- 标记物：
CD80 Antibody
- 宿主：
仓鼠
- 适应物种：
小鼠
- 免疫原：
CD80 Antibody
- 亚型：
CD80 Antibody
- 形态：
CD80 Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
25 µg/100 µg
| 规格： | 25 µg | 产品价格： | ￥1700.0 |
|---|---|---|---|
| 规格： | 100 µg | 产品价格： | ￥3900.0 |
Alexa Fluor® 488 anti-mouse CD80 Antibody详细如下：
Description ：CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is alsoknown as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells andmonocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation ofCD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendriticcells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cellactivation, proliferation, and cytokine production. CD80 appears to be expressed later in theimmune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliveran inhibitory signal to T cells.
Verified Reactivity ：Mouse
Reported Reactivity ：Dog
Antibody Type ：Monoclonal
Host Species ：Armenian Hamster
Immunogen ：CHO cell line transfected with mouse B7 (CD80)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Excitation Laser ：Blue Laser (488 nm)
Description ：CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is alsoknown as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells andmonocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation ofCD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendriticcells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cellactivation, proliferation, and cytokine production. CD80 appears to be expressed later in theimmune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliveran inhibitory signal to T cells.
Verified Reactivity ：Mouse
Reported Reactivity ：Dog
Antibody Type ：Monoclonal
Host Species ：Armenian Hamster
Immunogen ：CHO cell line transfected with mouse B7 (CD80)
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Excitation Laser ：Blue Laser (488 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicates BioLegend citation)
1. Harlan DM, et al. 1994. P. Natl. Acad. Sci. USA 91:3137. (IHC)
2. Razi-Wolf Z, et al. 1992. P. Natl. Acad. Sci. USA 89:4210. (Block, IP)
3. Hathcock KS, et al. 1994. J. Exp. Med. 180:631. (Block)
4. Herold KC, et al. 1997. J. Immunol. 158:984. (Block, IHC)
5. Ma XT, et al. 2006. Cancer Res. 66:1169.
6. Andoniou CE, et al. 2005. Nature Immunology 6:1011. (FC)
7. Lawson BR, et al. 2007. J. Immunol. 178:5366.
8. Turnquist HR, et al. 2007. J. Immunol. 178:7018.
9. Misra RS, et al. 2010. J. Exp Med. 207:1775. PubMed
10. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
11. Philipsen L, et al. 2013. Mol Cell Proteomics. 12:2551. PubMed
Product Citations：
1. Espinosa-Cueto P, et al. 2017. PLoS One.. 10.1371/journal.pone.0182126. PubMed
2. Philipsen L, et al. 2013. Mol Cell Proteomics. 12:2551. PubMed
3. Chanana P, et al. 2022. Cells. 11:. PubMed
4. Marangoni F, et al. 2021. Cell. . PubMed
5. Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
6. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
7. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
8. Chmielewski M and Abken H 2017. Cell Rep.. 10.1016/j.celrep.2017.11.063. PubMed
9. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
1. Harlan DM, et al. 1994. P. Natl. Acad. Sci. USA 91:3137. (IHC)
2. Razi-Wolf Z, et al. 1992. P. Natl. Acad. Sci. USA 89:4210. (Block, IP)
3. Hathcock KS, et al. 1994. J. Exp. Med. 180:631. (Block)
4. Herold KC, et al. 1997. J. Immunol. 158:984. (Block, IHC)
5. Ma XT, et al. 2006. Cancer Res. 66:1169.
6. Andoniou CE, et al. 2005. Nature Immunology 6:1011. (FC)
7. Lawson BR, et al. 2007. J. Immunol. 178:5366.
8. Turnquist HR, et al. 2007. J. Immunol. 178:7018.
9. Misra RS, et al. 2010. J. Exp Med. 207:1775. PubMed
10. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
11. Philipsen L, et al. 2013. Mol Cell Proteomics. 12:2551. PubMed
Product Citations：
1. Espinosa-Cueto P, et al. 2017. PLoS One.. 10.1371/journal.pone.0182126. PubMed
2. Philipsen L, et al. 2013. Mol Cell Proteomics. 12:2551. PubMed
3. Chanana P, et al. 2022. Cells. 11:. PubMed
4. Marangoni F, et al. 2021. Cell. . PubMed
5. Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
6. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
7. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
8. Chmielewski M and Abken H 2017. Cell Rep.. 10.1016/j.celrep.2017.11.063. PubMed
9. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
文献支持
Alexa Fluor® 488 抗小鼠 CD80 抗体
￥1700 - 3900
