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- PHR1030-500MG
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
有现货
- 英文名：
Tocopheryl Acetate, a
- CAS号：
7695-91-2
- 保质期：
根据瓶身LOT号查询
- 供应商：
浙江羽翔生物科技有限公司
- 保存条件：
2-8°C
- 规格：
500MG
属性
等级
certified reference material
pharmaceutical secondary standard
质量水平
300
Agency
traceable to Ph. Eur. T1600000
traceable to USP 1667701
API类
tocopherol
CofA
current certificate can be downloaded
技术
HPLC: suitable
gas chromatography (GC): suitable
密度
0.96 g/mL at 20 °C (lit.)
应用
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
SMILES字符串
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
InChI
1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
InChI key
ZAKOWWREFLAJOT-CEFNRUSXSA-N
一般描述
应用
分析说明
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文献和实验Long-term alpha-tocopherol supplements may improve mental development in extremely low birthweight infants.
Methods to improve the mental development of extremely low birthweight (ELBW) children are currently lacking. We assessed the effects of long-term supplementation of alpha-tocopherol on the neurological development of 259 school-aged ELBW children. Extremely low birthweight participants were divided into three groups: group A with no alpha-tocopherol supplementation (n = 121); group B with the supplementation for <6 months (n = 104) and group C with the supplementation for more than 6 months (n = 34). We analysed the participants' data at birth and between the ages of one-and-a-half to 8 years and evaluated potential factors associated with intellectual disabilities. Children from group C had the best outcome. The groups' mean gestational weeks and mean ventilator days were as follows: 27.5 weeks, 16.1 days (group A); 25.7 weeks, 41.7 days (group B); and 25.1 weeks, 75.5 days (group C). Multivariate regression analysis revealed that the odds ratios for impaired mental development at 8 years were 1.5 in group B and 0.19 (p = 0.017) in group C, compared with 1.0 in group A. The association between the duration of alpha-tocopherol administration and performance intelligence quotient (IQ) was dose dependent (p = 0.03). Long-term supplementation of alpha-tocopherol appeared to improve mental development, in particular, performance IQ, in school-aged ELBW children.
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