Purified 抗 CCL11（Eotaxin）抗体

Purified anti-CCL11 (Eotaxin) Antibody详细如下：

Description ：CCL11 is a member of the CC chemokine family and was originally identified as achemoattractant for eosinophils. In response to allergens, CCL11, which participates in avariety of allergic diseases, promotes accumulation of eosinophils. CCL11 production isupregulated in response to several proinflammatory cytokines, such as IL-4, IL-13, TNF-α, andIFN-α, produced by mast cells and Th2 lymphocytes. CCL11 has been reported to stimulateeosinophil release from bone marrow, resulting in an elevated level of circulating eosinophils.In addition, CCL11 facilitates proliferation and metastasis of tumor cells expressing the CCL11receptor, CCR3. CCL11 has been shown to induce an angiogenic response by CCR3-positivemicrovascular endothelial cells.

Verified Reactivity ：Human

Antibody Type ：Monoclonal

Host Species ：Rat

Immunogen ：Human CCL11 recombinant protein (Gly24-Pro97) expressed in E. coli

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation ：The antibody was purified by affinity chromatography.

Concentration ：0.5 mg/ml

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.

Application ：WB - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titratedfor optimal performance for each application.