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- 齐源
- 658709
- 国产/进口
- 2025年07月14日
- ICFC
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
9999
- 靶点：
Bcl-2
- 级别：
anti-Bcl-2 Antibody
- 目录编号：
anti-Bcl-2 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
anti-Bcl-2 Antibody
- 抗体英文名：
Brilliant Violet 421™ anti-Bcl-2 Antibody
- 抗体名：
Bcl-2 抗体
- 标记物：
anti-Bcl-2 Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
anti-Bcl-2 Antibody
- 亚型：
anti-Bcl-2 Antibody
- 形态：
anti-Bcl-2 Antibody
- 应用范围：
ICFC
- 保存条件：
2-8℃
- 浓度：
anti-Bcl-2 Antibody
- 规格：
25 tests
Brilliant Violet 421™ 抗 Bcl-2 抗体详细如下：
Description ：Bcl-2 is a conserved anti-apoptotic protein that plays important roles in normal immunity. Itforms homodimers or heterodimers with other Bcl-2 family members. This protein regulatesapoptosis through controlling mitochondrial fusion and fission. Phosphorylation of Bcl-2 hasbeen shown to enhance activity to allow response to extracellular growth-factor-mediatedsignals. Bcl-2 is also regulated by IRES, miR-15a, miR-16-1 and RNA-BP nucleolin.Chromosome 18q21.3 translocation and overexpression of Bcl-2 is frequently observed infollicular lymphomas and some diffuse large B-cell lymphomas.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation ：The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application： ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license fromSirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use thepurchased product for research purposes only. This product may not be resold or incorporated inany manner into another product for resale. Any use for therapeutics or diagnostics is strictlyprohibited. This product is covered by U.S. Patent(s), pending patent applications and foreignequivalents.
Excitation Laser ：Violet Laser (405 nm)
Description ：Bcl-2 is a conserved anti-apoptotic protein that plays important roles in normal immunity. Itforms homodimers or heterodimers with other Bcl-2 family members. This protein regulatesapoptosis through controlling mitochondrial fusion and fission. Phosphorylation of Bcl-2 hasbeen shown to enhance activity to allow response to extracellular growth-factor-mediatedsignals. Bcl-2 is also regulated by IRES, miR-15a, miR-16-1 and RNA-BP nucleolin.Chromosome 18q21.3 translocation and overexpression of Bcl-2 is frequently observed infollicular lymphomas and some diffuse large B-cell lymphomas.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation ：The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application： ICFC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by intracellular immunofluorescent staining withflow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl permillion cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license fromSirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use thepurchased product for research purposes only. This product may not be resold or incorporated inany manner into another product for resale. Any use for therapeutics or diagnostics is strictlyprohibited. This product is covered by U.S. Patent(s), pending patent applications and foreignequivalents.
Excitation Laser ：Violet Laser (405 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Pezzella F, et al. 1993. New Eng. J. Med. 329:690. (IHC)
2. Pezzella F, et al. 1990. Am. J. Pathol. 137:225. (IHC)
3. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
4. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
1. Pezzella F, et al. 1993. New Eng. J. Med. 329:690. (IHC)
2. Pezzella F, et al. 1990. Am. J. Pathol. 137:225. (IHC)
3. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
4. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
文献支持
Brilliant Violet 421™ Bcl-2 抗体
￥3900
