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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant fragment of human TIM3 protein
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX04440
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
IHC-P
- 浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
- 抗体英文名:
TIM-3 antibody [MSVA-366R] HistoMAX
- 抗体名:
TIM-3 抗体 [MSVA-366R] HistoMAX
- 规格:
500 μl
IHC-P analysis of human colon descendens mucosa tissue section using GTX04440 TIM-3 antibody [MSVA-366R] HistoMAX.
IHC-P analysis of human uterus cervix tissue section using GTX04440 TIM-3 antibody [MSVA-366R] HistoMAX.
TIM-3 negative squamous cell carcinoma showing a large number of TIM3 positive macrophages and also lymphocytes.
IHC-P analysis of human alveolar macrophages tissue section using GTX04440 TIM-3 antibody [MSVA-366R] HistoMAX.
Alveolar macrophages show strong TIM-3 immunostaining.
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文献和实验3敢和PD-1并驾齐驱,TIM3到底是何方神圣? TIM全名T淋巴细胞免疫球蛋白黏蛋白(T cell immunoglobulin mucin),还有个洋气的名字CD366,是2002年money等[6]在研究哮喘易感基因的过程中发现的。人类TIM家族只包括TIM1、TIM3和TIM4,位于5号染色体5q33.3上,TIM分子的共同结构包括:免疫球蛋白N末端可变区、粘蛋白结构域、跨膜区和胞内区。 图片来源于:http://www.genecards.org/cgi
重大进展!Science 同期两篇论文揭示 HIV-1 广谱性中和抗体的产生机制
设计」以及「定向诱导 B 细胞成熟」角度给出了解决方案。主要内容1. 「诱导广谱性中和抗体产生的通用疫苗设计策略」在题为《A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses》的文章中,William R. Schief 博士团队认为,大多数 HIV-1 广谱性中和抗体都是通过其重链的互补决定区 3(complementarity-determining region
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
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