- ￥4500
- 齐源
- 674502
- 国产/进口
- 2025年07月11日
- WB, ICFC, ICC
- 小鼠
- 人
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
IRF6
- 级别：
IRF6 Antibody
- 目录编号：
IRF6 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
IRF6 Antibody
- 抗体英文名：
Purified anti-IRF6 Antibody
- 抗体名：
IRF6 Antibody
- 标记物：
IRF6 Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
IRF6 Antibody
- 亚型：
IRF6 Antibody
- 形态：
IRF6 Antibody
- 应用范围：
WB, ICFC, ICC
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
100 µg
Purified anti-IRF6 Antibody详细如下：
Description ：IRF6 is a member of the IRF family of transcription factors, which are based on the presence ofthe conserved IRF tryptophan pentad repeat DNA-binding domain. Unlike other IRFtranscription factors, IRF6 is not involved in the expression of interferon genes and doesn’tseem to be involved in innate immunity. Data suggests that IRF6 is necessary for appropriateepidermal differentiation and development. Mutations of IRF6 are associated with humancraniofacial developmental defects such as cleft lip, palate, tooth agenesis, Van der Woudesyndrome, and popliteal pterygium syndrome. IRF6-deficient mice display severemorphological defects in skin and limbs, and result in perinatal lethality as well.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial human IRF6 recombinant protein (92-223 a.a.) expressed in E. coli.
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：WB - Quality tested、ICFC, ICC - Verified
Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested use of this reagent is 0.5 - 2.5 µg per ml. For intracellular flow cytometry using our TruePhos™ Perm Buffer in Cell Suspensions Protocol, the suggested use of this reagent is ≤1.0 µg permillion cells in 100 µl volume. For immunocytochemistry, a concentration range of 1.0 - 5.0 µg/ml isrecommended. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description ：IRF6 is a member of the IRF family of transcription factors, which are based on the presence ofthe conserved IRF tryptophan pentad repeat DNA-binding domain. Unlike other IRFtranscription factors, IRF6 is not involved in the expression of interferon genes and doesn’tseem to be involved in innate immunity. Data suggests that IRF6 is necessary for appropriateepidermal differentiation and development. Mutations of IRF6 are associated with humancraniofacial developmental defects such as cleft lip, palate, tooth agenesis, Van der Woudesyndrome, and popliteal pterygium syndrome. IRF6-deficient mice display severemorphological defects in skin and limbs, and result in perinatal lethality as well.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial human IRF6 recombinant protein (92-223 a.a.) expressed in E. coli.
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：WB - Quality tested、ICFC, ICC - Verified
Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested use of this reagent is 0.5 - 2.5 µg per ml. For intracellular flow cytometry using our TruePhos™ Perm Buffer in Cell Suspensions Protocol, the suggested use of this reagent is ≤1.0 µg permillion cells in 100 µl volume. For immunocytochemistry, a concentration range of 1.0 - 5.0 µg/ml isrecommended. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验该产品被引用文献
Product Citations：
1. Degen M, et al. 2018. Front Physiol. 9:1703. PubMed
2. Singh DR, et al. 2022. PLoS Pathog. 18:e1010868. PubMed
1. Degen M, et al. 2018. Front Physiol. 9:1703. PubMed
2. Singh DR, et al. 2022. PLoS Pathog. 18:e1010868. PubMed
文献支持
Purified 抗 IRF6 抗体
￥4500
