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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD40
- 级别:
CD40 Antibody
- 目录编号:
CD40 Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
CD40 Antibody
- 抗体英文名:
Ultra-LEAF™ Purified anti-mouse CD40 Antibody
- 抗体名:
CD40 Antibody
- 标记物:
CD40 Antibody
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
CD40 Antibody
- 亚型:
CD40 Antibody
- 形态:
CD40 Antibody
- 应用范围:
FC, Costim, Block, IP
- 保存条件:
2-8℃
- 浓度:
CD40 Antibody
- 规格:
100 µg/1 mg
| 规格: | 100 µg | 产品价格: | ¥3200.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥9900.0 |
Ultra-LEAF™ Purified anti-mouse CD40 Antibody详细如下:
Description :CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of thetumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelialcells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switchingand, in combination with other signals such as IL-4, protects B cells from surface Ig-inducedapoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), whichis expressed on activated T cells, is important in costimulation and immune regulation.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Formulation :0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxinlevel is <0.01 EU/µg of the protein (<0.001 ng/µg of the protein) as determined by the LAL test.
Preparation :The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration :The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentrationand expiration, please enter the lot number in our Certificate of Analysis online tool.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™solution contains no preservative; handle under aseptic conditions.
Application :FC - Quality tested、Costim, Block, IP - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cellsin 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.
Description :CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of thetumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelialcells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switchingand, in combination with other signals such as IL-4, protects B cells from surface Ig-inducedapoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), whichis expressed on activated T cells, is important in costimulation and immune regulation.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Formulation :0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxinlevel is <0.01 EU/µg of the protein (<0.001 ng/µg of the protein) as determined by the LAL test.
Preparation :The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration :The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentrationand expiration, please enter the lot number in our Certificate of Analysis online tool.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™solution contains no preservative; handle under aseptic conditions.
Application :FC - Quality tested、Costim, Block, IP - Reported in the literature, not verified in house
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cellsin 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Ferlin WG, et al. 1998. Eur. J. Immunol. 28:525. (FC, Costim)
2. Ferlin WG, et al. 1996. Eur. J. Immunol. 26:2911. (Costim)
3. Heath A, et al. 1994. Eur. J. Immunol. 24:1828. (Costim)
4. Ashman RF, et al. 2005. Int. Immunol. 17:411.
5. Pelßez B, et al. 2001. J. Immunol. 166:6608. (Block)
6. Zhang P, et al. 2007. J. Immunol. 178:474. (Block)
7. Lawson BR, et al. 2007. J. Immunol. 178:5366.
8. Ponomarev ED, et al. 2007. J.Immunol.178:39. PubMed
1. Ferlin WG, et al. 1998. Eur. J. Immunol. 28:525. (FC, Costim)
2. Ferlin WG, et al. 1996. Eur. J. Immunol. 26:2911. (Costim)
3. Heath A, et al. 1994. Eur. J. Immunol. 24:1828. (Costim)
4. Ashman RF, et al. 2005. Int. Immunol. 17:411.
5. Pelßez B, et al. 2001. J. Immunol. 166:6608. (Block)
6. Zhang P, et al. 2007. J. Immunol. 178:474. (Block)
7. Lawson BR, et al. 2007. J. Immunol. 178:5366.
8. Ponomarev ED, et al. 2007. J.Immunol.178:39. PubMed
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文献支持
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