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- 齐源
- 656009
- 国产/进口
- 2025年07月10日
- WB
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- 详细信息
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
IRF7
- 级别：
IRF7 Antibody
- 目录编号：
IRF7 Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
IRF7 Antibody
- 抗体英文名：
Direct-Blot™ HRP anti-IRF7 Antibody
- 抗体名：
IRF7 Antibody
- 标记物：
IRF7 Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
IRF7 Antibody
- 亚型：
IRF7 Antibody
- 形态：
IRF7 Antibody
- 应用范围：
WB
- 保存条件：
2-8℃
- 浓度：
IRF7 Antibody
- 规格：
100 µL
Direct-Blot™ HRP anti-IRF7 Antibody详细如下：
Description ：IRF-7 is a member of the interferon regulatory transcription factor family that plays keyregulatory roles in innate immunity. Upon virus infection, IRF-7 forms a complex with MyD88and TRAF6 when stimulated by toll-like receptors TLR7, TLR8, and TLR9, which in turn resultsin nuclear translocation and induction of interferon gene expression. IRF-7 gene expression isupregulated by the stimulation of interferon through the Jak-STAT signaling pathway, whichforms a positive feedback loop. The protein level of IRF-7 after activation is thendownregulated by the ubiquitin-proteasome system to avoid excessive production ofinterferons that may cause damage to the host. Virus induced type I interferon expression wascompletely abrogated in IRF-7 knockout mice, suggesting that IRF-7 is critical for interferonmediated host defense during virus infection.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial IRF7 recombinant protein (127-503 a.a.)
Formulation ：This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation ：The antibody was purified by affinity chromatography and conjugated with HRP under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected fromprolonged exposure to light.
Application ：WB - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested dilution is 1:2000-1:8000. The optimal dilution should be determined by titration for eachindividual assay of interest.
25 µl and 100 µl of Direct-Blot™ HRP antibody can be used for approximately 5 and 20 Westernblots, respectively, at the recommended concentration/dilution.
Description ：IRF-7 is a member of the interferon regulatory transcription factor family that plays keyregulatory roles in innate immunity. Upon virus infection, IRF-7 forms a complex with MyD88and TRAF6 when stimulated by toll-like receptors TLR7, TLR8, and TLR9, which in turn resultsin nuclear translocation and induction of interferon gene expression. IRF-7 gene expression isupregulated by the stimulation of interferon through the Jak-STAT signaling pathway, whichforms a positive feedback loop. The protein level of IRF-7 after activation is thendownregulated by the ubiquitin-proteasome system to avoid excessive production ofinterferons that may cause damage to the host. Virus induced type I interferon expression wascompletely abrogated in IRF-7 knockout mice, suggesting that IRF-7 is critical for interferonmediated host defense during virus infection.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Partial IRF7 recombinant protein (127-503 a.a.)
Formulation ：This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation ：The antibody was purified by affinity chromatography and conjugated with HRP under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected fromprolonged exposure to light.
Application ：WB - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by Western blotting. For Western blotting, thesuggested dilution is 1:2000-1:8000. The optimal dilution should be determined by titration for eachindividual assay of interest.
25 µl and 100 µl of Direct-Blot™ HRP antibody can be used for approximately 5 and 20 Westernblots, respectively, at the recommended concentration/dilution.
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Direct-Blot™ HRP 抗 IRF7 抗体
￥5800
