Purified 抗人 CD184 (CXCR4) 抗体

Purified anti-human CD184 (CXCR4) Antibody详细如下：

Description ：CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXCchemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and Tcells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets,lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons,among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates bloodcell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, bloodvessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and analternative receptor for some isolates of HIV-2.

Verified Reactivity ：Human, Cynomolgus, Rhesus

Reported Reactivity ：African Green, Baboon, Chimpanzee, Sooty Mangabey

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：CP-MAC-infected Sup-T1 cells

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation ：The antibody was purified by affinity chromatography

Concentration ：0.5 mg/mL

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.

Application ：FC - Quality tested、ICC, CyTOF® - Verified、IHC - Reported in the literature, not verified in house

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10 cells in100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimalperformance for each application.