Description :Histone H3 is phosphorylated at serine 10 during mitosis and is found to be involved intranscriptional activation, chromatin decondensation, and chromosome compaction during celldivision, by the action of Aurora kinase and NIMA kinases.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :Modified synthetic peptide conjugated to KLH
Formulation :This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.05% sodium azide.
Preparation :The antibody was purified by antigen-affinity chromatography.
Concentration :0.5 mg/ml
Storage & Handling :Upon receipt, store undiluted between 2°C and 8°C.
Application :WB - Quality tested、IF - Verified
Recommended Usage :Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggestedworking dilution(s): Use 1 µg per ml antibody dilution buffer for each mini-gel. It is recommendedthat the reagent be titrated for optimal performance for each application.
Application Notes :The histone H3 pS10 antibody recognizes phosphorylation of human H3 protein at Ser10 residueand has been shown to be useful for Western blotting.