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- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD207
- 级别：
anti-human CD207 (Langerin) Antibody
- 目录编号：
anti-human CD207 (Langerin) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
anti-human CD207 (Langerin) Antibody
- 抗体英文名：
TotalSeq™-C0403 anti-human CD207 (Langerin) Antibody
- 抗体名：
CD207 (Langerin) Antibody
- 标记物：
anti-human CD207 (Langerin) Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
anti-human CD207 (Langerin) Antibody
- 亚型：
anti-human CD207 (Langerin) Antibody
- 形态：
anti-human CD207 (Langerin) Antibody
- 应用范围：
PG
- 保存条件：
2-8℃
- 浓度：
0.5 mg/mL
- 规格：
10 ug
Description ：CD207, also known as Langerin, is a 40 kD type II transmemberane cell glycoprotein whichbelongs to C-type lectin with mannose binding specificity. It is predominantly expressed onLangerhans cells and induces the formation of Birbeck granules, the Langerhans cell hallmarkorganelle. It is also found on several other subtypes of dendritic cells, such as dermal CD103-positive dendritic cells and splenic CD8-positive dendritic cells. Langerin is generally thought tobe involved in antigen processing. Recently, it has been found that HIV captured by Langerinwas internalized into Birbeck granule and degraded, which results in inhibition of HIV-1 infectionand subsequent transmission.
Verified Reactivity ：Human
Reported Reactivity ：Cynomolgus
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Primary human Langerhans cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 1 mM EDTA
Preparation ：The antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer underoptimal conditions.
Concentration ：0.5 mg/mL
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application ：PG - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis and the oligomer sequence is confirmed by sequencing. TotalSeq™-C antibodies arecompatible with 10x Genomics Chromium Single Cell Immune Profiling Solution.
To maximize performance, it is strongly recommended that the reagent be titrated for eachapplication, and that you centrifuge the antibody dilution before adding to the cells at 14,000xg at 2- 8°C for 10 minutes. Carefully pipette out the liquid avoiding the bottom of the tube and add to thecell suspension. For Proteogenomics analysis, the suggested starting amount of this reagent fortitration is ≤ 1.0 µg per million cells in 100 µL volume. Refer to the corresponding TotalSeq™protocol for specific staining instructions.
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文献和实验1. Witte LD, et al. 2007. Nat. Med. 13:367. (Block)
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