Description :CD70, also known as CD27L, is a 50 kD type II transmembrane glycoprotein and member ofthe tumor necrosis factor superfamily. CD70 is expressed on activated T, B and NK cells,activated plasmacytoid dendritic cells (pDCs), and chronic B cell lymphocytic leukemia andlarge B cell lymphomas. CD70 costimulates T cell proliferation and differentiation. It plays a rolein the pDC-induced B cell differentiation. The ligand of CD70 is CD27.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :CD70-transfected L cells
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 underoptimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in100 µL staining volume or 5 µL per 100 µL of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.