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文献和实验Mechanical Stretch-Induced Signal Transduction in Cultured Mesangial Cells
transmitter of mechanical signals, is required for activation of Erk and its upstream kinase Raf-1. The GTPase RhoA, a central regulator of the actin cytoskeleton, is also activated by stretch, and both Erk activation and subsequent matrix upregulation
Mitochondrial DNA Oxidative Damage and Mutagenesis in Saccharomyces cerevisiae
with age and are therefore believed to contribute to aging and age-related pathology. Housed within the mitochondrial matrix, mtDNA encodes several of the proteins involved in the production of ATP via the process of oxidative phosphorylation
v468.chapter 1 经典 Wnt/b-Catenin 信号通路 (英文完整版)
. 1.3 ). Many of these co-activator proteins, such as the histoneacetylase CREB-binding protein (CBP), Brahma-related gene (BRG)-1(a component of the SWI/SNF chromatin remodelling complex),and Hyrax interact directly with the C-terminus of β-catenin. Another protein, Pygopus
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