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文献和实验【求助】factor-related apoptosis inducing ligand和TNF-α
wzmchxz 求助各位战友： factor-related apoptosis inducing ligand指的是什么，它和TNF-α的关系？ 感谢您的帮助。 kern6549 你这个不完整吧，应该是tumor necrosis factor(TNF)-related apoptosis inducing ligand。 这个分子简称TRAIL，与相应受体结合后能够诱导细胞凋亡。 目前，诱导
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
, TNF-related apoptosis-inducing ligand (TRAIL), or Apo-2 ligand, has generated excitement because of its unique ability to induce apoptosis in a wide range of transformed cell lines but not in normal tissues. TRAIL is well tolerated when given
In 1995, the tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) was identified on the basis of sequence homology to the other members of the TNF family (1 ). Like TNF and CD95 ligand (CD95L/FasL/ APO-1L), TRAIL (APO-2L
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