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文献和实验Typing of Tumor Necrosis Factor Alleles
The tumor necrosis factor (TNF) locus contains the three closely related cytokine genes: TNF , and lymphotoxin α and �. The gene cluster lies at the telomeric end of the class III region of the major histocompatibility complex (MHC
Hematopoiesis is the process of blood cell formation in the adult human, the bone marrow (BM) is the primary hematopoietic organ. Each day, the BM produces billions of leukocytes, erythrocytes, and thrombocytes, which enter the circulation
Collagen-Induced Arthritis in Mice: A Major Role for Tumor Necrosis Factor-
arthritis, including tumor necrosis factor-α (TNFα) and interleukin (IL)-1β, IL-6, IL-1Ra, IL-10, and transforming growth factor β. The use transgenic and knockout strains of mice, as well as biological inhibitors, have revealed important pathological roles
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