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文献和实验Genomic Strategies for the Identification of Dopamine Receptor Genes in Zebrafish
In this chapter, we describe the identification and cloning of D2-like dopamine receptor (DR) genes in zebrafish, a vertebrate model genetic organism. To identify DR genes, we performed searches of the zebrafish genomic sequence database
Characterization of Dopamine Receptors
of the radioligand's molar concentration is also included. Keywords: Receptor binding; dopamine; D1; D2; D3; D4; D5; radioligand binding GO TO THE FULL PROTOCOL:
Overview of Receptor Allosterism
/competitive interactions. (A ) Inhibition of [3 H]spiperone binding by methylisobutylamiloride (MIA) at dopamine D2 receptors in membranes from Ltk59 cells. The dotted line corresponds to a curve fit based on the simple allosteric ternary complex model (Eq
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