Human DNA Methyltransferase 1

DamIP: Using Mutant DNA Adenine Methyltransferase to Study DNA‐Protein Interactions In Vivo

for studying DNA?protein interaction in vivo. A mutant form of DNA adenine methyltransferase (DamK9A) from E. coli is fused to the protein of interest and expressed. The fusion protein will bind to target binding sites and introduce N 6 ?adenine methylation

Detection of Methyl′Sensitive DNA′Binding Proteins with Possible Involvement in the Imprinting Phenomenon

methyltransferase 1 (Dnmt1) 1 . Recently two new methyltransferases have been identified, Dnmt2 and Dnmt3 2 ,3 , but it remains unclear which of these enzymes has de novo activity and differentially methylates imprinted genes. Parent′specific methylation patterns

Simultaneous Single‐Molecule Mapping of Protein‐DNA Interactions and DNA Methylation by MAPit

methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase. J. Biol. Chem. 280:64‐72.    Vyhlidal, C., Samudio, I., Kladde, M.P., and Safe, S. 2000. Transcriptional