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- 2025年07月12日
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文献和实验c-kit Mutational Analysis in Paraffin Material
-oncogene in extracutaneous organs. The receptor molecule KIT is a potential therapeutic target for tyrosine kinase inhibitors. KIT mutations have been described in more than 80% of SM, but only in the minority of cutaneous mastocytoses (CM). Usually exon 17
Cell Motility, Adhesion, Homing, and Migration Assays in the Studies of Tyrosine Kinases
, including c-Kit and c-Met receptors (5 ). The downstream targets of these kinases can involve cytoskeletal proteins which are important in cell motility, cell migration and invasion. It is also known that the tyrosine kinase oncogene BCR/ABL
Anti-c-erb-B-2 Ribozyme for Breast Cancer
Our laboratory has investigated the cleavage activity of an-anti-c-erb -B-2 ribozyme. The c-erb -B-2 proto-oncogene (also called HER-2/neu ) encodes a 185 kDa transmembrane tyrosine kinase-type receptor that is homologous with the epidermal
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