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文献和实验Acute myeloid leukemia (AML) has an annual incidence of 2.4 cases per 100,000 persons and is the most common form of acute leukemia in adults (1 , 2 ). AML is a model for drug-resistant human cancers, and current therapies for AML possess
Generation of Dendritic Cells from Rat Bone Marrow
could not be provided in vitro (3 ,4 ). The availability of recombinant cytokines and the observations that DC in culture are dependent on cytokines such as granulocyte-macrophage colony-stimulating factor (GM-CSF) (5 ,6 ) and IL-4 (7 ,8 ) have revolutionized DC
Granulocyte-macrophage colony-stimulating factor (GM-CSF), a 23-kDa polypeptide, was originally identified as a hematopoietic growth factor, but has recently been found to be a multifunctional cytokine with many proinflammatory activities
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