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文献和实验Collagen-Induced Arthritis in Mice
with autologous or heterologous type II collagen in complete Freund’s adjuvant and susceptibility to the disease is strongly associated with major histocompatibility complex class II genes. The development of collagen-induced arthritis is associated with strong T
Recombinant Collagen Trimers from Insect Cells and Yeast
. Some of the fibril-forming collagens are now in medical use, in applications ranging from the use of type I collagen as a biomaterial and a delivery system for several drugs to trials for the potential of type II collagen as an oral tolerance-inducing agent
in the circulation, and their levels are believed to reflect type II collagen synthesis. In this chapter we describe the development of a specific enzyme-linked immunosorbent assay (ELISA) for the measurement of the IIA form of PIINP (PIIANP) in serum based
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