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文献和实验and polypeptides that can be targeted at bacterial prey. This includes the bactericidal/permeability-increasing protein (BPI), a cytotoxic protein that at nM concentrations acts selectively against many Gram-negative bacteria. The principal determinant
Neutralization of the In Vivo Activity of E. Coli-Derived Lipopolysaccharide by Cationic Peptides
, an outer membrane component of Gram-negative bacteria, is a necessary step for the antibacterial activity of CAP37 (cationic antimicrobial protein of 37 kDa molecular weight) (1 ,2 ), bactericidal permeability increasing protein (BPI/CAP57) (3 ), and CAP
Identifying Small‐Molecule Modulators of Protein‐Protein Interactions
interactions. Nat. Biotechnol. 18:847‐851. Ramani, A.K., Bunescu, R.C., Mooney, R.J., and Marcotte, E.M. 2005. Consolidating the set of known human protein‐protein interactions
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