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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD207
- 级别：
anti-human CD207 (Langerin) Antibody
- 目录编号：
anti-human CD207 (Langerin) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
anti-human CD207 (Langerin) Antibody
- 抗体英文名：
anti-human CD207 (Langerin) Antibody-APC
- 抗体名：
CD207 抗体
- 标记物：
APC
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
anti-human CD207 (Langerin) Antibody
- 亚型：
anti-human CD207 (Langerin) Antibody
- 形态：
anti-human CD207 (Langerin) Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
anti-human CD207 (Langerin) Antibody
- 规格：
25 tests/100 tests
| 规格： | 25 tests | 产品价格： | ￥2500.0 |
|---|---|---|---|
| 规格： | 100 tests | 产品价格： | ￥6100.0 |
Description ：CD207, also known as Langerin, is a 40 kD type II transmemberane cell glycoprotein whichbelongs to C-type lectin with mannose binding specificity. It is predominantly expressed onLangerhans cells and induces the formation of Birbeck granules, the Langerhans cell hallmarkorganelle. It is also found on several other subtypes of dendritic cells, such as dermal CD103-positive dendritic cells and splenic CD8-positive dendritic cells. Langerin is generally thought tobe involved in antigen processing. Recently, it has been found that HIV captured by Langerinwas internalized into Birbeck granule and degraded, which results in inhibition of HIV-1 infectionand subsequent transmission.
Verified Reactivity ：Human
Reported Reactivity ：Cynomolgus
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Primary human Langerhans cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Red Laser (633 nm)
Application Notes ：Additional reported application (for the relevant formats) includes: blocking the binding of HIV-1 toLangerhans cells .
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文献和实验1. Witte LD, et al. 2007. Nat. Med. 13:367. (Block)
Product Citations：
1. Xu Y, et al. 2021. Cell Reports. 36(6):109524. PubMed
抗体二抗上连接有荧光染料。直接标记染色背景低，实验程序少尽量减少实验工序和过程，以保证实验的真实和准确性。因此在条件允许的范围内，建议尽量用直接标记的抗体进行实验。 3、流式抗体荧光标记的选择： 如果实验中检测单一指标：不同荧光标记在不同的仪器上强度不同。以某仪器为例：PE ＞APC ＞PE-Cy5 ＞PerCP ＞FITC ＞PerCP-Cy5.5，通常来说，PE最强，适用于弱表达抗原。FITC强度较弱，适用于强表达抗原，使用范围比较广。用户需根据检测的目标蛋白进行具体选择。 如果同时检测多个
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