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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
Ser727
- 级别:
PhosphoPair STAT1 (Ser727) Antibody Set
- 目录编号:
PhosphoPair STAT1 (Ser727) Antibody Set
- 克隆性:
单克隆
- 抗原来源:
PhosphoPair STAT1 (Ser727) Antibody Set
- 保质期:
PhosphoPair STAT1 (Ser727) Antibody Set
- 抗体英文名:
PhosphoPair STAT1 (Ser727) Antibody Set
- 抗体名:
Ser727 抗体
- 标记物:
PhosphoPair STAT1 (Ser727) Antibody Set
- 宿主:
PhosphoPair STAT1 (Ser727) Antibody Set
- 适应物种:
小鼠、人
- 免疫原:
PhosphoPair STAT1 (Ser727) Antibody Set
- 亚型:
PhosphoPair STAT1 (Ser727) Antibody Set
- 形态:
PhosphoPair STAT1 (Ser727) Antibody Set
- 应用范围:
WB
- 保存条件:
2-8℃
- 浓度:
PhosphoPair STAT1 (Ser727) Antibody Set
- 规格:
1 kit
PhosphoPair STAT1 (Ser727) Antibody Set详细如下:
Description :STAT1, also known as signal transduction and activator of transcription 1, is a ubiquitouslyexpressed cytoplasmic protein and is activated in response to cytokine signaling, including IFNα, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated by receptorassociated kinases, translocates to the nucleus, and functions as a transcription factor.Phosphorylation at serine 727 is required for full transcriptional activator function. Twoisoforms of STAT1, with apparent molecular weights of 88 (STAT1α) and 91 (STAT1β) kD,exist as a result of alternative RNA processing. STAT1 is involved in IFN-mediated immuneresponses, and STAT1-deficient mice are highly sensitive to bacterial and viral infections.
Verified Reactivity :Human, Mouse
Immunogen :Please refer to individual product datasheets for immunogen information
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation :The antibody was purified by affinity chromatography.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :WB - Quality testeed
Recommended Usage :Each lot of antibodies in this set is quality control tested by Western blotting. For Western blotting,the suggested uses of these reagents are as follows:
Clone 10C4B40: 1.0 µg/mL
Clone A15158B: 0.5 - 2.5 µg/mL
It is recommended that the reagent be titrated for optimal performance for each application.
Description :STAT1, also known as signal transduction and activator of transcription 1, is a ubiquitouslyexpressed cytoplasmic protein and is activated in response to cytokine signaling, including IFNα, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated by receptorassociated kinases, translocates to the nucleus, and functions as a transcription factor.Phosphorylation at serine 727 is required for full transcriptional activator function. Twoisoforms of STAT1, with apparent molecular weights of 88 (STAT1α) and 91 (STAT1β) kD,exist as a result of alternative RNA processing. STAT1 is involved in IFN-mediated immuneresponses, and STAT1-deficient mice are highly sensitive to bacterial and viral infections.
Verified Reactivity :Human, Mouse
Immunogen :Please refer to individual product datasheets for immunogen information
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation :The antibody was purified by affinity chromatography.
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C.
Application :WB - Quality testeed
Recommended Usage :Each lot of antibodies in this set is quality control tested by Western blotting. For Western blotting,the suggested uses of these reagents are as follows:
Clone 10C4B40: 1.0 µg/mL
Clone A15158B: 0.5 - 2.5 µg/mL
It is recommended that the reagent be titrated for optimal performance for each application.
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文献和实验该产品被引用文献
Antigen References:
1. Durbin JE, et al. 1996. Cell. 84:443-50.
2. Darnell JE Jr, et al. 1994. Science. 264:1415-21.
3. Chen X, et al. 1998. Cell. 93:827-39.
4. Ramana CV, et al. 2000. Oncogene. 19:2619-27.
1. Durbin JE, et al. 1996. Cell. 84:443-50.
2. Darnell JE Jr, et al. 1994. Science. 264:1415-21.
3. Chen X, et al. 1998. Cell. 93:827-39.
4. Ramana CV, et al. 2000. Oncogene. 19:2619-27.
文献支持
PhosphoPair STAT1 (Ser727) 抗体 试剂盒
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