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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD117
- 级别：
anti-human CD117 (c-kit) Antibody
- 目录编号：
anti-human CD117 (c-kit) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
anti-human CD117 (c-kit) Antibody
- 抗体英文名：
Alexa Fluor® 488 anti-human CD117 (c-kit) Antibody
- 抗体名：
CD117 Antibody
- 标记物：
anti-human CD117 (c-kit) Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
anti-human CD117 (c-kit) Antibody
- 亚型：
anti-human CD117 (c-kit) Antibody
- 形态：
anti-human CD117 (c-kit) Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
anti-human CD117 (c-kit) Antibody
- 规格：
25 tests/100 tests
| 规格： | 25 tests | 产品价格： | ￥2600.0 |
|---|---|---|---|
| 规格： | 100 tests | 产品价格： | ￥5500.0 |
Description ：CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cellfactor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells(approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML).CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferationand survival of primitive hematopoietic stem cells as well as erythroid-committed and granulomonocytic committed cells.
Verified Reactivity ：Human
Reported Reactivity ：Cynomolgus, Cow
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：MOLM-1 megakaryocytic cell line
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
SB - Reported in the literature, not verified in house
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
Excitation Laser ：Blue Laser (488 nm)
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文献和实验1. Broudy VC, et al. 1999. Blood 94:1979. (IF, IP)
2. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
3. Nagano M, et al. 2007. Blood 110:151. (FC) PubMed
4. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
5. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
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