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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
β-Methylglutaconic acid
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
5746-90-7
- 规格：
5 mg/10 mg/25 mg
| 规格： | 5 mg | 产品价格： | ￥250.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥400.0 |
| 规格： | 25 mg | 产品价格： | ￥800.0 |
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3-Methylglutaconic acid
CAS No. : 5746-90-7
MCE 国际站：3-Methylglutaconic acid
产品活性：3-Methylglutaconic acid 是3-甲基戊二酸尿症 (MGTA) 中积累的主要代谢物。3-Methylglutaconic acid 能诱导脂质氧化损伤和蛋白质氧化损伤，降低大脑皮层上清液的非酶促抗氧化防御能力，引起大脑皮层氧化应激。3-Methylglutaconic acid 可用于大脑损伤疾病的研究。
研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling | Others
作用靶点：GABA Receptor | Others
In Vitro: 3-Methylglutaconic acid (0.1-5.0 mM, 1 h) induces lipid oxidative damage and antioxidants (TRO, MEL and SOD plus CAT) prevent the lipid peroxidation at higher doses of 5 mM in rat cerebral cortex supernatants.
3-Methylglutaconic acid (0.1-5.0 mM, 1 h) induces protein oxidative damage and diminishes non-enzymatic antioxidant defenses in rat cerebral cortex supernatants.
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文献和实验Phosphoamino acid analysis:Mark Kamps's method
.The blotters should be quite damp,but not soaking wet. 10.Rotate 90° counter clockwise.Electrophorese at pH 3.5,1.6 KV,13 min in the second dimension. The above electrophoresis times are appropriate when you are using a Salk/TVL/MBVL type electrophoresis rig
Phosphoamino acid analysis:Mark Kamps method
Phosphoamino acid analysis:Mark Kamps's method 1. Label your protein with 32Pi. Then subject the protein to SDS polyacrylamide gel electrophoresis and transfer your gel-fractionated protein to Immobilon-P .
Two dimensional peptide mapping
. Note that the recipe in Wade's paper is wrong. The pH should be adjusted to 8.90 with either NH4OH or CO2 Don't use the 98% formic acid and don't adjust the pH.
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