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5-LOX-IN-5
MCE 国际站：5-LOX-IN-5
产品活性：5-LOX-IN-5 (Compound 29) 是一种 5-LOX 抑制剂 (IC50: 56 nM)。5-LOX-IN-5 可用于神经退行性疾病的研究。
研究领域：Metabolic Enzyme/Protease
作用靶点：Lipoxygenase
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文献和实验The Cre/Lox System to Assess the Development of the Mouse Brain
Cre-mediated recombination has become a powerful tool to confine gene deletions (conditional knockouts) or overexpression of genes (conditional knockin/overexpression). By spatiotemporal restriction of genetic manipulations, major problems
The CRE/lox System as a Tool for Developmental Studies at the Cell and Tissue Level
can elucidate its exact role in a specific region within a certain time frame. Implementation of several site-specific recombination systems such as CRE/lox has created powerful tools to study the role of many genes at the cellular level. In this chapter
Use of Cre-Lox Technology to Analyze Integrin Functions in Astrocytes
and signaling. Specifically, we will detail how Cre-lox molecular genetic techniques have revealed important roles for integrin αvβ8 in regulating cerebral blood vessel development and homeostasis. First, we will detail how to generate
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