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- BioLegend
- 909801
- BioLegend
- 2026年01月01日
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- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
BioLegend 909801 Purified Non-muscle Myosin Heavy Chain II-A
- 供应商：
北京云肽生物科技有限公司
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 909801 Purified Non-muscle Myosin Heavy Chain II-A
产品简介：
产品品牌：BioLegend
产品货号：909801
产品名称：BioLegend 909801 Purified Non-muscle Myosin Heavy Chain II-A
产品规格：100 µL
产品说明：
Clone Poly19098 (See other available formats)
Regulatory Status RUO
Other Names
Myosin-9, NMMHC-A, MYH9 variant protein, myosin heavy chain 9, non-muscle myosin heavy chain A, cellular myosin heavy chain, type A, non-muscle myosin heavy polypeptide 9
Previously Covance Catalog# PRB-440P
Isotype Rabbit Polyclonal IgG
描述
非肌肉肌球蛋白重链II-A是肌球蛋白超家族的一员。肌球蛋白II有三种形式，称为肌球蛋白IIA、肌球蛋白IIB和肌球蛋白IIC。这些蛋白质参与细胞运动、细胞形状的维持和胞质分裂。每种类型的肌球蛋白II蛋白由两条重链和四条轻链组成。每个重链有两个部分：肌球蛋白头状结构域和尾部区域。头部区域与肌动蛋白相互作用，肌动蛋白是一种对细胞运动和形状很重要的蛋白质。长尾区与其他蛋白质相互作用，包括其他肌球蛋白的尾部区域。
Non-muscle Myosin Heavy Chain II-A is a member of the myosin superfamily. There are three forms of myosin II, called myosin IIA, myosin IIB and myosin IIC. These proteins are involved in cell motility, maintenance of cell shape, and cytokinesis. Each type of myosin II protein consists of two heavy chains and four light chains. The heavy chains each have two parts: a myosin head-like domain and a tail region. The head region interacts with actin, a protein that is important for cell movement and shape. The long tail region interacts with other proteins, including the tail regions of other myosin proteins.
Product Details
Verified Reactivity Human, Mouse, Rat
Reported Reactivity Cow
Antibody Type Polyclonal
Host Species Rabbit
Immunogen
This antibody was raised against the peptide GKADGAEAKPAE corresponding to the C-terminus of human nonmuscle myosin heavy chain isoform A (MHC-A, NMHC IIA, Myosin-9).
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration 1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application WB - Quality tested
ICC - Verified
Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 2.0 µg per ml (1:500 - 1:1000 dilution). For immunocytochemistry, a concentration range of 0.5 - 1.0 μg/ml (1:500 - 1:1000 dilution) is recommended. The recommended usage for this polyclonal antibody may vary from lot to lot. It is recommended that the reagent be titrated for optimal performance for each application.
Antigen Details
Biology Area
Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
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文献和实验【求助】请教：myosin 2 和 nonmuscle myosin2有何区别
between the head and tail. These light chains are often referred to as the essential light chain and the regulatory light chain. In muscle cells, it is myosin II that is responsible for producing the contractile force. Here, the long coiled-coil tails
Purification of Myosin Light Chain Kinase
should be injected (ear vein)with ~5 cc of nembutal solution and then exsanguinated and skinned.Skeletal muscle should be cleaned of fat and connective tissue and kept on ice. 2.The tissue should be ground in the cold room using the fine setting of the meat grinder
Isolation and Culture of Human Airway Smooth Muscle Cells
doublings and express smooth muscle cell-specific markers such as myosin heavy chain, myosin light chain kinase, α-actin, caldesmon, and SM22α . In addition, the synthetic function of these cells appears to be comparable to those studied in vivo
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