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- 英文名：
PE/Fire™ 640 anti-human CD38
- 供应商：
北京云肽生物科技有限公司
BioLegend 397218 PE/Fire™ 640 anti-human CD38
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 397218 PE/Fire™ 640 anti-human CD38
产品简介：
产品品牌：BioLegend
产品货号：397218
产品名称：BioLegend 397218 PE/Fire™ 640 anti-human CD38
产品规格：100 tests
产品说明：
Clone S17015F (See other available formats)
Regulatory Status RUO
Other Names HB7, T10, ADP-ribosyl cyclase
Isotype Mouse IgG2a, κ
描述
CD38是一种45 kD II型跨膜糖蛋白，也称为T10。它是一种ADP-核糖基水解酶，在造血细胞和一些非造血组织（如脑、肌肉和肾脏）中以不同水平表达。在人类中，它在浆细胞和活化的T和B细胞上以高水平表达。通过作为环化酶和水解酶，CD38介导淋巴细胞活化，粘附以及cADPR和NAADP的代谢。CD31是CD38的配体。
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Product Details
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen Human CD38 transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Fire™ 640 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Fire™ 640 has a maximum excitation of 566 nm and a maximum emission of 639 nm.
Antigen Details
Structure
ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
Distribution
T cells, B cells, NK, myeloid, plasma, and dendritic cells
Function
Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
Ligand/Receptor CD31, hyaluronic acid
Cell Type
B cells, Dendritic cells, NK cells, Plasma cells, T cells
Biology Area Cell Adhesion, Cell Biology, Immunology
Molecular Family Adhesion Molecules, CD Molecules
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BioLegend 397218 PE/Fire™ 640 anti-human CD38
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