产品说明: Clone QA17A27 (See other available formats) Regulatory Status RUO Other Names B4 Isotype Mouse IgG1, κ
描述 CD19是一种95kD的糖蛋白,也称为B4。它是Ig超家族的一员,在所有B至成熟B细胞(发育过程中)和滤泡树突状细胞上表达。浆细胞不表达CD19。CD19与CD21和CD81结合,形成与B细胞活化整合的分子复合物。 CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.
Product Details Verified Reactivity Mouse Antibody Type Recombinant Host Species Mouse Immunogen Mouse CD19-expressing K562 human erythroleukemia cells Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide Preparation The antibody was purified by affinity chromatography and conjugated with Spark Violet™ 423 under optimal conditions. Concentration 0.5 mg/mL Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. Application FC - Quality tested
Recommended Usage Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Spark Violet™ 423 has a maximum excitation of 400 nm and a maximum emission of 415 nm.
Excitation Laser Violet Laser (405 nm) Application Notes Clone QA17A27 of antibody can block binding of 6D5 clone on target and vice versa.
Antigen Details Structure Ig superfamily, associates with CD21 and CD81, 95 kD Distribution Pro-B cells to mature B cells (during development), follicular dendritic cells
Function Modulates B cell activation and differentiation Interaction B cells, Dendritic cells Ligand/Receptor CD21, CD81, Leu-13 Cell Type B cells, Dendritic cells Biology Area Costimulatory Molecules, Immunology Molecular Family CD Molecules
以下是BioLegend 品牌部分产品,如需其他产品请联系本公司销售。 BioLegend 134332 PE/Dazzle™ 594 anti-mouse FcεRIα 44986 100 ug BioLegend 134402 Purified anti-mouse lymphotoxin beta receptor (LTβR) 5G11 100 ug BioLegend 134403 PE anti-mouse lymphotoxin beta receptor (LTβR) 5G11 25 ug BioLegend 134605 PE anti-mouse Ly108 330-AJ 25 ug BioLegend 134606 PE anti-mouse Ly108 330-AJ 100 ug BioLegend 134608 Pacific Blue™ anti-mouse Ly108 330-AJ 100 ug BioLegend 134609 APC anti-mouse Ly108 330-AJ 25 ug BioLegend 134610 APC anti-mouse Ly108 330-AJ 100 ug BioLegend 134701 Purified anti-mouse CD146 ME-9F1 50 ug BioLegend 134704 PE anti-mouse CD146 ME-9F1 100 ug BioLegend 134705 FITC anti-mouse CD146 ME-9F1 25 ug BioLegend 134711 APC anti-mouse CD146 ME-9F1 25 ug BioLegend 134712 APC anti-mouse CD146 ME-9F1 100 ug BioLegend 134714 PE/Cyanine7 anti-mouse CD146 ME-9F1 100 ug BioLegend 134716 Biotin anti-mouse CD146 ME-9F1 100 ug BioLegend 134905 PE anti-mouse TCR Vδ4 GL2 25 ug BioLegend 135002 Purified anti-mouse CD127 (IL-7Rα) A7R34 500 ug BioLegend 135005 Biotin anti-mouse CD127 (IL-7Rα) A7R34 50 ug BioLegend 135006 Biotin anti-mouse CD127 (IL-7Rα) A7R34 500 ug BioLegend 135007 FITC anti-mouse CD127 (IL-7Rα) A7R34 50 ug BioLegend 135009 PE anti-mouse CD127 (IL-7Rα) A7R34 50 ug BioLegend 135011 APC anti-mouse CD127 (IL-7Rα) A7R34 25 ug