相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 库存:
99
- 英文名:
Ultra-LEAF™ Purified anti-mouse CD20
- 供应商:
北京云肽生物科技有限公司
北京云肽生物科技有限公司作为BioLegend的特约经销商,为广大客户提供原装正品,货期短,折扣好的服务准则。
美国BioLegend公司位于美国加州,致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长,但它聚集了一批来自PharMingen公司的专业人士,建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势,以及与世界知名实验室和研究所的良好合作关系,以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证,提供各种质量卓越的产品,并不断地开发新产品,以满足飞速发展的生命科学研究的需要。
BioLegend 152115 Ultra-LEAF™ Purified anti-mouse CD20
产品简介:
产品品牌:BioLegend
产品货号:152115
产品名称:BioLegend 152115 Ultra-LEAF™ Purified anti-mouse CD20
产品规格:5 mg
产品说明:
Clone SA271G2 (See other available formats)
Regulatory Status RUO
Other Names Ms4a1, Ly-44
IsotypeRat IgG2b, κ
描述
CD20是一种33-37kD的蛋白质,是MS4A家族的一员,具有四个跨膜区,当与MHC I类和II类、CD53、CD81和CD82结合时,这些跨膜区在细胞表面以同源寡聚复合物的形式存在。CD20在B细胞和T细胞亚群上表达,但在浆细胞上不表达。CD20调节B细胞的活化和增殖。其连接促进跨膜Ca2+运输。CD20是治疗B细胞淋巴瘤和白血病的重要治疗靶点。
CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.
Product Details
Isotype Control
Ultra-LEAF™ Purified Rat IgG2b, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Mouse CD20 transfected cells
Formulation
0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/µg of the protein (<0.001 ng/µg of the protein) as determined by the LAL test.
Preparation
The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Concentration
The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Application FC - Quality tested
Depletion - Verified
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Clone SA271G2 has been validated for in vivo depletion of mouse B cells.
Additional Product Notes
View more applications data for this product in our Scientific Poster Library.
Watch a Scientific Poster video of this product.
Antigen Details
Structure
Member of the MS4A family, four transmembrane spanning regions, three isoforms of 37, 35, and 37 kD, depending on the phosphorylation degree.
Distribution B cells and a subset of T cells
Function Regulates B-cell activation and proliferation
Interaction
Associates with MHC class I and II, CD53, CD81, and CD82
Cell Type B cells, T cells
Biology Area Costimulatory Molecules, Immunology
Molecular Family CD Molecules
以下是BioLegend 品牌部分产品,如需其他产品请联系本公司销售。
BioLegend 128307 PE anti-mouse DLL1 HMD1-3 50 ug
BioLegend 128601 Purified anti-mouse CD34 HM34 50 ug
BioLegend 128608 PerCP/Cyanine5.5 anti-mouse CD34 HM34 100 ug
BioLegend 128609 PE anti-mouse CD34 HM34 50 ug
BioLegend 128610 PE anti-mouse CD34 HM34 200 ug
BioLegend 128611 APC anti-mouse CD34 HM34 25 ug
BioLegend 128612 APC anti-mouse CD34 HM34 100 ug
BioLegend 128618 PE/Cyanine7 anti-mouse CD34 HM34 100 ug
BioLegend 128621 APC/Cyanine7 anti-mouse CD34 HM34 25 ug
BioLegend 128622 APC/Cyanine7 anti-mouse CD34 HM34 100 ug
BioLegend 128710 PE anti-mouse CD199 (CCR9) CW-1.2 100 ug
BioLegend 128712 PE/Cyanine7 anti-mouse CD199 (CCR9) CW-1.2 100 ug
BioLegend 128805 PE anti-mouse CD226 (DNAM-1) 1000000 25 ug
BioLegend 128810 APC anti-mouse CD226 (DNAM-1) 1000000 100 ug
BioLegend 128812 PE/Cyanine7 anti-mouse CD226 (DNAM-1) 1000000 100 ug
BioLegend 128813 PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1) 1000000 25 ug
BioLegend 128814 PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1) 1000000 100 ug
BioLegend 128822 Purified anti-mouse CD226 (DNAM-1) 1000000 500 ug
BioLegend 129602 Purified anti-mouse Siglec H 551 500 ug
BioLegend 129605 PE anti-mouse Siglec H 551 25 ug
BioLegend 129606 PE anti-mouse Siglec H 551 100 ug
BioLegend 129608 Alexa Fluor® 647 anti-mouse Siglec H 551 100 ug
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
- 作者
- 内容
- 询问日期
文献和实验7211011 小鼠淋巴细胞分离液 达优 100339 Ultra-LEAF™ Purified anti-mouse CD3ε Antibody BioLegend 102115 Ultra-LEAF™ Purified anti-mouse CD28 Antibody BioLegend CD3/CD28 Streptamer® 多聚体法: 货号 名称
Cell Surface Immunofluorescence Staining Protocol
. In the mouse, purified anti-mouse CD16/CD32 antibody specific for Fcγ R III/II (BioLegend Cat. #101302, clone 93) can be used to block nonspecific staining of antibodies. In this case, block Fc receptors by pre-incubating cells with 5-10 μg/ml purified anti-CD
全基因组的比较基因组杂交技术介绍(Whole-Genome and Custom Fine-Tiling Array CGH)
or many different regions of interest).Key features of NimbleGen’s microarrays - ultra-high density and long oligo probes - yield a powerful, high-definition CGH platform for whole genome analysis. With the flexibility of NimbleGen array synthesis, chromosomal
技术资料暂无技术资料 索取技术资料









