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BioLegend 152115 Ultra-LEAF™ P

urified anti-mouse CD20
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  • BioLegend
  • 152115
  • BioLegend
  • 2025年10月26日
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    • 英文名

      Ultra-LEAF™ Purified anti-mouse CD20

    • 供应商

      北京云肽生物科技有限公司

    BioLegend 152115 Ultra-LEAF™ Purified anti-mouse CD20

    北京云肽生物科技有限公司作为BioLegend的特约经销商,为广大客户提供原装正品,货期短,折扣好的服务准则。

    美国BioLegend公司位于美国加州,致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长,但它聚集了一批来自PharMingen公司的专业人士,建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势,以及与世界知名实验室和研究所的良好合作关系,以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证,提供各种质量卓越的产品,并不断地开发新产品,以满足飞速发展的生命科学研究的需要。

    BioLegend 152115 Ultra-LEAF™ Purified anti-mouse CD20
    产品简介:
    产品品牌:BioLegend
    产品货号:152115
    产品名称:BioLegend 152115 Ultra-LEAF™ Purified anti-mouse CD20
    产品规格:5 mg

    产品说明:
    Clone  SA271G2 (See other available formats)
    Regulatory Status  RUO
    Other Names  Ms4a1, Ly-44
    IsotypeRat  IgG2b, κ

    描述
    CD20是一种33-37kD的蛋白质,是MS4A家族的一员,具有四个跨膜区,当与MHC I类和II类、CD53、CD81和CD82结合时,这些跨膜区在细胞表面以同源寡聚复合物的形式存在。CD20在B细胞和T细胞亚群上表达,但在浆细胞上不表达。CD20调节B细胞的活化和增殖。其连接促进跨膜Ca2+运输。CD20是治疗B细胞淋巴瘤和白血病的重要治疗靶点。
    CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.

    Product Details
    Isotype Control
    Ultra-LEAF™ Purified Rat IgG2b, κ Isotype Ctrl
    Verified Reactivity  Mouse
    Antibody Type  Monoclonal
    Host Species  Rat
    Immunogen  Mouse CD20 transfected cells

    Formulation
    0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/µg of the protein (<0.001 ng/µg of the protein) as determined by the LAL test.

    Preparation
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    Concentration
    The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.

    Storage & Handling
    The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
    Application  FC - Quality tested
    Depletion - Verified

    Recommended Usage
    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Clone SA271G2 has been validated for in vivo depletion of mouse B cells.
    Additional Product Notes
    View more applications data for this product in our Scientific Poster Library.

    Watch a Scientific Poster video of this product.

    Antigen Details
    Structure
    Member of the MS4A family, four transmembrane spanning regions, three isoforms of 37, 35, and 37 kD, depending on the phosphorylation degree.
    Distribution  B cells and a subset of T cells

    Function  Regulates B-cell activation and proliferation
    Interaction
    Associates with MHC class I and II, CD53, CD81, and CD82
    Cell Type  B cells, T cells
    Biology Area  Costimulatory Molecules, Immunology
    Molecular Family  CD Molecules

    以下是BioLegend  品牌部分产品,如需其他产品请联系本公司销售。
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    BioLegend 128609 PE anti-mouse CD34  HM34  50 ug
    BioLegend 128610 PE anti-mouse CD34  HM34  200 ug
    BioLegend 128611 APC anti-mouse CD34     HM34  25 ug
    BioLegend 128612 APC anti-mouse CD34     HM34  100 ug
    BioLegend 128618 PE/Cyanine7 anti-mouse CD34   HM34  100 ug
    BioLegend 128621 APC/Cyanine7 anti-mouse CD34 HM34  25 ug
    BioLegend 128622 APC/Cyanine7 anti-mouse CD34 HM34  100 ug
    BioLegend 128710 PE anti-mouse CD199 (CCR9) CW-1.2      100 ug
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    BioLegend 128805 PE anti-mouse CD226 (DNAM-1) 1000000    25 ug
    BioLegend 128810 APC anti-mouse CD226 (DNAM-1)    1000000    100 ug
    BioLegend 128812 PE/Cyanine7 anti-mouse CD226 (DNAM-1)  1000000    100 ug
    BioLegend 128813 PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1)     1000000    25 ug
    BioLegend 128814 PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1)     1000000    100 ug
    BioLegend 128822 Purified anti-mouse CD226 (DNAM-1)    1000000    500 ug
    BioLegend 129602 Purified anti-mouse Siglec H 551      500 ug
    BioLegend 129605 PE anti-mouse Siglec H    551      25 ug
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