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- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
PE anti-human TLR7
- 供应商：
北京云肽生物科技有限公司
BioLegend 376903 PE anti-human TLR7
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
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BioLegend 376903 PE anti-human TLR7
产品简介：
产品品牌：BioLegend
产品货号：376903
产品名称：BioLegend 376903 PE anti-human TLR7
产品规格：25 tests
产品说明：
Clone S18024F (See other available formats)
Regulatory Status RUO
Other Names Toll-like receptor (TLR) 7, CD287
Isotype Rat IgG2a, κ
描述
Toll样受体（TLR）7，也称为CD287，是一种1型跨膜蛋白，是TLR受体家族的成员。TLR7在浆细胞样树突状细胞、骨髓细胞和B淋巴细胞中细胞内表达，并通过结合单链RNA（ssRNA）在先天免疫应答中起重要作用。TLR7通过MyD88发出信号，导致IFN-α / β和其他炎性细胞因子的激活和分泌。
Toll-like receptor (TLR) 7, also known as CD287 is a type 1 transmembrane protein, member of the TLR receptor family. TLR7 is expressed intracellularly in plasmacytoid dendritic cells, myeloid cells, and B lymphocytes and plays an important role in the innate immune response by binding single-stranded RNA (ssRNA). TLR7 signals through MyD88, which leads to the activation and secretion of IFN-α/β and other inflammatory cytokines.
Product Details
Isotype Control PE Rat IgG2a, κ Isotype Ctrl
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application ICFC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Antigen Details
Structure
Type 1 transmembrane protein, member of the Toll-like receptor (TLR) family
Distribution
Expressed intracellularly in plasmacytoid dendritic cells, myeloid cells, and B lymphocytes, Monocytes
Function
Pattern recognition receptor that detects single-stranded RNA, induces proinflammatory cytokine production
Interaction B cells, Dendritic cells
Ligand/Receptor Single-stranded RNA
Cell Type B cells, Dendritic cells
Biology Area Immunology, Innate Immunity
Molecular Family CD Molecules, Innate Immune Signaling
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BioLegend 376903 PE anti-human TLR7
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