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- 2025年10月23日
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- 库存：
99
- 英文名：
PE anti-mouse CD79a (Igα)
- 供应商：
北京云肽生物科技有限公司
北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 133103 PE anti-mouse CD79a (Igα)
产品简介：
产品品牌：BioLegend
产品货号：133103
产品名称：BioLegend 133103 PE anti-mouse CD79a (Igα)
产品规格：50 µg
产品说明：
Clone F11-172 (See other available formats)
Regulatory Status RUO
Other Names Mb-1, Igα
Isotype Armenian Hamster IgG
描述
小鼠CD79a（Igα链）是一种47 kD的I型整合膜蛋白，称为mb-1或Igα。它与CD79b（Igβ链）形成异二聚体。CD79a和CD79b异二聚体与表面IgM结合以形成成熟B细胞中通过BCR进行信号转导所必需的B细胞受体（BCR）。CD79a可能在介导IgM向细胞表面的转运中发挥作用。克隆F11-172抗体识别存在于B淋巴细胞上的47kD膜糖蛋白。
Mouse CD79a (Ig α chain) is a 47 kD type I integral membrane protein, known as mb-1 or Ig α. It forms a heterodimer with CD79b (Ig β chain). The CD79a and CD79b heterodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79a may play a role in mediating the transport of IgM to the cell surface. Clone F11-172 antibody recognizes the 47 kD membrane glycoprotein present on B lymphocytes.
Product Details
Isotype Control PE Armenian Hamster IgG Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Armenian Hamster
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application ICFC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Antigen Details
Structure
A 47 kD membrane glycoprotein which associates with CD79b to form part of B-cell receptor complex.
Distribution
CD79a is expressed on B cells at various differentiation stages, from pre-B cell to plasma cells. It is expressed probably before expression of cytoplasmic µu chain.
Function Mediating the transport of IgM to the cell surface.
Ligand/Receptor
CD79a/CD79b heterodimers are associated with surface IgM to form B cell receptor complex (BCR) to recognize specific antigen.
Cell Type B cells, Plasma cells
Biology Area Immunology
Molecular Family CD Molecules
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